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Longitudinal evaluation of cryolipolysis efficacy

Wellaholic Research: Longitudinal evaluation of cryolipolysis efficacy

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Cryolipolysis Efficacy: Longitudinal Study Results

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3-4 cm

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2-3 Mths

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Direct Answer: How Long Do Cryolipolysis Results Last?

The article explores the durability of cryolipolysis, a non-invasive fat reduction method. Limited case studies 🔬 suggest that fat reduction via cryolipolysis is durable at 2-5 years post-treatment, even with body weight fluctuations. These findings are supported by observations that asymmetries between treated and untreated areas persist over time 👀. While larger, prospective trials are needed for broader populations, historical data indicates that cryolipolysis induces adipocyte apoptosis and a natural clearing process lasting up to four months 💪. This suggests the effects are long-lasting, with no new fat deposition reversing the procedure’s benefits in the observed subjects ✅.

Background

Have you ever wondered about the long-term effects of fat-freezing treatments?

As leading aesthetic professionals with years of experience in Singapore, we’ve observed the soaring popularity of cryolipolysis, or ‘fat freezing,’ at Wellaholic outlets across the island and throughout the body contouring industry. Our customers often ask us about the lasting results of this non-invasive fat reduction method. At Wellaholic, our commitment to scientific efficacy means we don’t just follow external research; we actively conduct internal studies and rigorously track client outcomes. Our data, compiled from thousands of WellaFreeze™ 360 sessions across Singapore, reinforces the findings of leading dermatological journals, ensuring our clients receive treatments backed by both global and local evidence.

In this article, we’ll share our insights on a longitudinal study that evaluates the effectiveness of this treatment over time. We’ll break down the key findings and what they mean for anyone considering cryolipolysis as a fat reduction option.

In the bustling city of Singapore, a woman is availing the state-of-the-art WellaFreeze 360 fat freeze treatment at Wellaholic. This revolutionary treatment is designed to assist individuals in their journey towards achieving their desired body shape by targeting and eliminating stubborn fat cells through a process of controlled cooling. The WellaFreeze 360 fat freeze treatment is a non-surgical procedure that employs the principle of cryolipolysis to freeze and destroy fat cells, leaving the surrounding tissues unaffected. The body then naturally metabolizes and expels these dead cells over time, resulting in a more defined and contoured physique. The efficacy of the WellaFreeze 360 fat freeze treatment is well-documented. Numerous customers have reported noticeable changes after just a handful of sessions, making it a sought-after choice for those in pursuit of a safe and effective fat reduction technique.

Introduction

In Singapore’s bustling urban environment and vibrant food scene, maintaining a desired body shape can be challenging. Stubborn fat pockets that resist conventional diet and exercise negatively impact body image and confidence. While liposuction remains a popular option for body contouring Singapore, this surgical procedure involves inherent risks and recovery downtime. The growing demand for non-invasive slimming treatments Singapore has inspired innovative alternatives using various technologies including radiofrequency, ultrasound, laser, and controlled cooling.

One breakthrough in non-invasive fat freezing Singapore is cryolipolysis, commonly known as “fat freezing.” This technique safely and effectively reduces unwanted fat by using controlled cooling to target fat cells. Research shows that fat cells are more sensitive to cold than surrounding tissues like skin or muscle. Scientists discovered decades ago that fat tissue could be selectively reduced through cold exposure without harming other structures. Early studies confirmed that controlled skin cooling could trigger a natural fat removal process, making fat freezing a viable body sculpting Singapore solution.

The first such fat freezing study among Chinese individuals in 2012 showed promising results, with a single session of cryolipolysis leading to an 81% improvement in the treatment area after 2 months.

Fat removal through controlled cooling works because fat cells are less resistant to cold than skin. After treatment, the body naturally responds by triggering a gentle inflammatory process—this is the body’s way of clearing out the frozen fat cells. Within 3 days, the body begins breaking down these fat cells. Over the next 14-30 days, the body’s cleanup cells (macrophages) actively digest and remove the damaged fat. By 90 days, the inflammation has resolved, and the fat cells are completely eliminated through the body’s natural processes. Safety studies confirm that blood lipid levels and liver function remain normal throughout this 3-month fat reduction period.

Multiple research studies have confirmed that a single fat freezing session produces visible fat layer reduction. In Dover’s landmark study of 32 participants, one side of the body was treated with a controlled cooling process (the treatment uses a programmed cooling intensity to safely freeze fat cells), while the other side served as a comparison. Ultrasound measurements showed an average fat layer reduction of 22.4% at 4 months post-treatment. The best results were seen in participants with modest, localized fat bulges. Importantly, no adverse events were reported and 94% of participants experienced minimal or expected discomfort during treatment. At 6 months, 80% of subjects were satisfied with their fat freezing Singapore results.

Additional research confirms these promising fat reduction results:

  • Riopelle’s Study: Measured 5 male participants and reported an 18.2% fat layer reduction at 6 months post-treatment.
  • Coleman’s Study: Treated 9 participants and found 20.4% fat reduction at 2 months, increasing to 25.5% at 6 months.
  • Shek’s Study: Demonstrated statistically significant fat layer reduction in 21 participants after a single treatment.

These consistent findings across multiple studies reinforce that cryolipolysis delivers reliable, measurable fat reduction for body sculpting Singapore clients.

There have been no reports to date that provide evaluation of efficacy beyond 6-month post-treatment, which may reflect the fact that this treatment is relatively new or simply that longer follow-up periods add cost and compliance issues. These case studies provide information about the long-term efficacy of cryolipolysis by visual comparison of baseline and late follow-up photos of treated and un-treated control areas in two subjects. To demonstrate the longevity of cryolipolysis for fat layer reduction, larger, prospective trials are needed which follow subjects 1–5 years after treatment.

Pre- and post-treatment images showing fat layer reduction on the patient’s left (treated) flank at 2-year post-treatment. (a)
The image was taken prior to the procedure, and (b) the image was taken 2 years after the procedure.
In the bustling city of Singapore, a man is availing the state-of-the-art WellaFreeze 360 fat freeze treatment at Wellaholic. This revolutionary treatment is designed to assist individuals in their journey towards achieving their desired body shape by targeting and eliminating stubborn fat cells through a process of controlled cooling. The WellaFreeze 360 fat freeze treatment is a non-surgical procedure that employs the principle of cryolipolysis to freeze and destroy fat cells, leaving the surrounding tissues unaffected. The body then naturally metabolizes and expels these dead cells over time, resulting in a more defined and contoured physique. The efficacy of the WellaFreeze 360 fat freeze treatment is well-documented. Numerous customers have reported noticeable changes after just a handful of sessions, making it a sought-after choice for those in pursuit of a safe and effective fat reduction technique.

Conclusion

While clinical studies indicate cryolipolysis treatment results in an average of approximately 20% fat layer
reduction, the durability of these results had not previously been evaluated. These case studies support the finding that fat reduction via cryolipolysis is durable at 2- 5-years post-treatment in this very small sample size, even in the presence of fluctuations in body weight.

These case studies suggest that once fat cells are eliminated through cryolipolysis, new fat doesn’t grow back in treated areas over time. The differences between treated and untreated sides remain visible years later. The treatment works by triggering fat cell death (apoptosis), followed by the body’s natural removal process taking up to 4 months. While these findings are promising for Singaporeans considering fat freezing, larger long-term studies are needed to confirm results across broader populations. The main challenge for such studies is finding participants willing to leave one side untreated for extended periods. Nonetheless, current evidence supports cryolipolysis as a reliable long-term body contouring Singapore solution when combined with a healthy lifestyle.

Source

Willie Chan - Portrait

Willie Chan, Founder (LinkedIn)

Willie Chan, Founder & Managing Director (LinkedIn, Member of the Singapore Association of Spa & Wellness Professionals). A highly respected figure in Singapore’s aesthetic industry with over a decade of experience in body contouring and fat reduction treatments, Willie’s leadership at Wellaholic has earned multiple local awards including recognition from Daily Vanity and Beauty Insider for innovative body contouring solutions. His CIDESCO Diploma in Aesthetics and certification in Beauty Therapy & Salon Management from Brentwood College UK ensure treatments are grounded in accredited aesthetic science. Willie’s expertise in non-invasive fat freezing Singapore techniques, combined with his commitment to data-driven results from thousands of client sessions across Wellaholic’s outlets island-wide, has established him as a trusted authority in fat freezing and slimming treatments Singapore.

Contact Willie at willie@wellaholic.com


Serene Chiam - Portrait

Serene Chiam, Aesthetic Director (LinkedIn)

Serene Chiam, Aesthetic Director (LinkedIn). A leading authority in Singapore’s body sculpting Singapore scene, Serene brings over ten years of expertise in fat freezing treatments and has helped thousands of clients achieve their body goals through cutting-edge technologies like WellaFreeze™ 360 cryolipolysis. Her CIDESCO certificate in skincare and Bachelor of Health Science (Aesthetics) from Torrens University of Australia showcase her dedication to evidence-based treatments. Having previously served as a Clinical Aesthetics Manager with Laser Clinics Australia, Serene actively contributes to Wellaholic’s internal research protocols and client outcome tracking across all Singapore outlets. Serene’s extensive background in the aesthetics industry has solidified her reputation as a trusted expert in non-surgical fat reduction solutions for Singaporeans seeking effective slimming treatments Singapore without surgery or downtime.

Contact Serene at serene@wellaholic.com

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  • 360° Surround Cooling Technology. The handles or cooling cups can be adjusted to fit all body curves and contouring for best freezing.
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  • Shorter Time Needed. Each duration is reduced from typical 60 minutes to just 30 minutes.
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Wellaholic Research: A Longitudinal Evaluation of Cryolipolysis Efficacy in Singapore’s Body Contouring Scene

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